Medication-Assisted Treatment (MAT)

MAT involves the use of medicines along with counseling and behavior therapies. It is effective in treating opioid use disorders (OUD) and is used to support patients during the recovery period. Medical research recognizes OUD as an illness with chronic, long-lasting effects. As more patients recover from OUD with medical therapy advances, researchers continue to search for new and more efficient treatments.

Three FDA-approved drugs are used to treat opioid dependence, including naltrexone, buprenorphine, and methadone. These treatments are considered to be effective and safe when combined with talk therapy and psychosocial supports. Patients who seek recovery from an OUD should have access to MAT, counseling, and behavioral supports. Because OUD is a chronic illness, patients should be regularly re-evaluated for continued MAT.

There is no defined duration for maintenance treatments. For some patients, MAT may be used for an indefinite period as needed.

brain-explode-01

FDA-approved buprenorphine and naloxone medicines used for the treatment of OUD, including:

  • Buprenorphine/naloxone (Bunavail) buccal film
  • Buprenorphine/naloxone (Cassipa) sub-lingual film
  • Buprenorphine extended-release (Sublocade) injection (subcutaneous use)
  • Buprenorphine subdermal implant (Probuphine)
  • Buprenorphine/naloxone (Zubsolv) sub-lingual tabs

FDA-approved methadone medicines used for the treatment of OUD, including:

  • Methadone hydrochloride (Dolophine) tabs
  • Methadone hydrochloride (Methadose) oral concentration

FDA-approved naltrexone medicines used for the treatment of OUD, including:

  • Naltrexone (Vivitrol) extended-release suspension by IM injection

There is no defined duration for maintenance treatments. For some patients, MAT may be used for an indefinite period as needed.

Scroll to Top